|
Home
What is
Hepatitis
How is it
Transmitted
Long Term
Prognosis
Complications of
HCV
Liver
Biopsy
Treatment Info
(Interferon, Herbal, etc)
Lab Tests (PCR,
Genotype,etc.)
Nutrition
& Alternative Info
Patient
Information (Support Groups, Doctor Listing,
etc)
Related
Webpages
Transplant
Info
Site
Search
HCV
Webrings
My
guestbookbook
Site
Awards
FAQ &
Disclaimers
|
Duration of HCV infection as a predictor of NonResponse to
Interferon
Duration of hepatitis C virus (HCV) infection is a key feature
in determining responsiveness to interferon (IFN). Studies
assessing its value as a predictive factor in chronic HCV infection
show that a long duration of infection reduces the likelihood of a
sustained response to IFN (defined as ALT normalization and
clearance of serum HCV-RNA). The effect of HCV infection duration
is independent of the presence of cirrhosis and level of HCV
viremia. Meta-analysis of IFN trials in acute HCV infection shows
an obvious effect of the drug on long-term ALT normalization and
HCV-RNA clearance. Treatment of HCV infection during the acute or
early chronic phase could therefore maximize therapeutic
effectiveness.
Author: CRAXI A, POLICLIN UNIV, DIV MED & GASTROENTEROL,
MED CLIN 1, PIAZZA CLIN 2, I-90100 PALERMO, ITALY
Source: DIGESTIVE DISEASES AND SCIENCES 1996 DEC;41(12):S 86-S
92
Home | What is HCV | Transmission |
Future |
Complications |
Biopsy |
Treatment
| Lab |
Nutrition |
Patient |
Links | Transplant |
Webrings |
guestbookbook |
Awards |
FAQ
|
|