|
Home
What is
Hepatitis
How is it
Transmitted
Long Term
Prognosis
Complications of
HCV
Liver
Biopsy
Treatment Info
(Interferon, Herbal, etc)
Lab Tests (PCR,
Genotype,etc.)
Nutrition
& Alternative Info
Patient
Information (Support Groups, Doctor Listing,
etc)
Related
Webpages
Transplant
Info
Site
Search
HCV
Webrings
My
guestbookbook
Site
Awards
FAQ &
Disclaimers
|
The influence of age on the prevalence of hepatitis C virus
subtypes 1a and 1b
The distribution of hepatitis C virus (HCV) genotypes was
determined in isolates of 447 chronically HCV-infected German
patients by nucleotide sequencing. Of these, 206 (46.1%) were
infected with the subtype 1a, 215 (48.1%) with subtype 1b, 2 (0.4%)
with subtype 1c, 9 (2.0%) with subtype 3a, and 15 (3.4%) with
subtype 4a. Subtype 1a was predominant in those < 40 years old
(62.6%) and was associated with the risk factor of intravenous drug
addiction and with shorter duration of disease. Conversely, subtype
1b was more frequent in patients > 50 years old (84.7%; P <
.001) and was associated with the risk factor of blood transfusions
and with longer duration of disease. These data suggest that a
shift from subtype 1b to subtype 1a occurred in the population
studied. An increase in HCV infection with subtype 1a and a
diminution of subtype 1b in the future can be expected.
Author: Feucht HH, Schroter M, Zollner B, Polywka S, Nolte H,
Laufs R Institute of Medical Microbiology and Immunology,
Universitatskrankenhaus Eppendorf, Hamburg, Germany.
Source: J Infect Dis 175: 685-688 (1997)
Home | What is HCV | Transmission |
Future |
Complications |
Biopsy |
Treatment
| Lab |
Nutrition |
Patient |
Links | Transplant |
Webrings |
guestbookbook |
Awards |
FAQ
|
|