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BLOOD GLUTAMIC-PYRUVIC TRANSAMINASE (SGPT)

Purpose of the test:
Helps detect and evaluate treatment of acute hepatic disease
Helps distinguish between myocardial and hepatic-tissue damage

Preparation:
Don't eat any food or drink any liquid for at least 12 hours before the test.

Time before test results available:
Test requires only a few minutes in the laboratory. Time before results are reported to the doctor or patient varies from a few minutes to a few days.

Normal values:
Men--10 to 32 u/liter
Women--9 to 24u/liter
Infants--Twice normal range of adults

What "high" or "increased" may indicate:
Severe hepatitis
Chronic hepatitis
Early or improving acute viral hepatitis
Infectious mononucleosis
Intrahepatic cholestasis
Cholecystitis
Severe hepatic congestion due to heart failure
Slight to moderately high levels may indicate any condition that produces acute hepatocellular injury.

Taking these drugs may affect test results:
Barbiturates
Chlorpromazine
Codeine
Griseofulvin
Isoniazid
Meperidine
Methyldopa
Morphine
Narcotic analgesics
Nitrofurantoin
Para-aminosalicylic acid
Phenothiazines
Phenytoin
Salicylates
Tetracycline

Other factors that may affect test results:
Eating lead
Exposure to carbon tetrachloride
Failure to fast overnight
If tourniquet is applied on the arm too long (over 1 minute), it may cause an inaccurate test result. Request another sample to be collected to ensure accuracy.


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