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Am J Med 1996 Jan;100(1):41-45
Occupational risk of hepatitis C infections among general dentists
and oral surgeons in North America.
by Thomas DL, Gruninger SE, Siew C, Joy ED, Quinn TC
PURPOSE: To assess the occupational risk of hepatitis C virus
(HCV) infection among dental personnel. METHODS: Three hundred
forty-three oral surgeons and 305 general dentists were recruited
at national meetings of the American Dental Association and matched
by gender, age, years of practice, and location of practice. Each
participant completed a detailed questionnaire designated to
measure occupational risk of blood-borne infections and supplied a
sample of blood. Antibodies to HCV (anti-HCV) were assessed by
second-generation enzyme immunoassay and recombinant immunoblot
assay. As a marker of occupational exposure to blood-borne viruses,
hepatitis B virus (HBV) surface antigen and antibodies to HBV
surface and core antigens were measured by enzyme immunoassay.
RESULTS: Anti-HCV was found in 2.0% of oral surgeons and 0.7% of
general dentists (odds ratio [OR] = 3.2, P = 0.133). Anti-HCV was
more prevalent (P less than 0.01) in dental personnel who were
older, had more years of practice, and had serologic markers of HBV
infection. Serologic markers of HBV infection were found in 7.8% of
general dentists and 21.2% of oral surgeons (OR 3.1, P less than
0.001). CONCLUSIONS: These data confirm high rates of HBV infection
among dental personnel, but suggest that the risk of HCV infection
is considerably lower.
PMID: 8579085, UI: 96164809
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