Risks for transmission of hepatitis C virus during artificial
insemination
Fertil Steril 66 (1): 161-163 (1996)
McKee TA, Avery S, Majid A, Brinsden PR
Department of Pathology, Cambridge University, United
Kingdom.
OBJECTIVE:
To identify risks of hepatitis C virus transmission by semen from
infected donors.
DESIGN:
Case report. SETTING: Assisted fertility clinic.
PATIENTS:
Hepatitis C virus-infected semen donor and recipients of his
donations.
INTERVENTION:
Testing for hepatitis C virus by serology and polymerase chain
reaction.
MAIN OUTCOME MEASURES:
Detection of hepatitis C virus antibodies and viral RNA.
RESULTS:
Hepatitis C virus RNA was detected in the semen donation before but
not after purification; none of the recipients of the donors
samples were found to have antibodies to hepatitis C virus.
CONCLUSIONS:
Hepatitis C virus RNA can be detected in semen donations from
infected donors; purification of donations before insemination
significantly reduces the amount of viral RNA in the semen
pellet.
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